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KMID : 0043319900130020187
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Archives of Pharmacal Research
1990 Volume.13 No. 2 p.187 ~ p.191
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Synthesis of Some Heterocycles of Potential Biological Activity
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Harb AEA
Mostafa FH/Metwally SA
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Abstract
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A convenient method for the preparation of imidazobenzimidazole 3, imidazoimidazole 5, imidazotriazole 6 and pyrano [2, 3-c] oxazole 7 derivatives is described. This depends on interaction of 2-methyl-4-arylidene-2-oxazolin-5-ones 1 with o-diamines, thiosemicarbazide and/or ethylcyanoacetate. The effect of alcoholic potassium cyanide on oxazolinone 1 was studied. Antibacterial activity of the obtained products was studied.
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